Latest insights on Imidazolate-based nanomaterials for various applications: A state-of-the-art review.

Materials Today Communications, SCIE, Q2

Trần Thanh Tâm Toàn, Dong A University, Danang city 550000, Viet Nam

Abstract

In the latest generations, nanosized metal-organic frameworks – a unique class of organic-inorganic hybridized coordinating polymeric nanomaterials – have shown considerable potential in biomedicine. ZIFs (mean zeolitic imidazolate frameworks), a distinct subclass group made of metallic cations and imidazolate connectors, and have distinct merits like great porous, a huge surface zone, strong biocompatibility properties, pH sensitivity characteristics and others. These make ZIFs appealing and attempting carriers for delivering different cargos of medications, imaging reagents and bio-large molecules for detecting and treating cancer disease. In addition, this work describes the latest studies on imidazolate-nanomaterials for biosensors applications, tumor imaging devices and light theranostic use. The various methods for creating ZIF-based nanosized materials, characterizing and functionalizing them be updated and first reviewed. Imidazolate materials such as electrochemical reactions, fluorescent procedures, and colorimetric sensing play crucial roles in biosensing. Next, ZIF-mediated both mono and/or multi-mode tumor image approaches are discussed. Special focus is given to tumor light theranostics applications based on imidazole-nanoscale, which offer viable other routes to significantly raise the therapeutic activity of tumor disease. Lastly, the potential benefits and drawbacks of imidazolates nanomaterials from the perspective of novel medications are suggested and mentioned.

DOI: https://doi.org/10.1016/j.mtcomm.2023.107243