Asian Journal of Chemistry
Comparative Study on Bioactivities of Four Rose Species for Anti-aging Cosmetic Applications
Xuan-Tien Le, Minh-Chau Huynh-Bao, Huong-Thao Nguyen-Huynh, and Tuan-Anh Trieu
When the skin is exposed to UVA/UVB rays, it stimulates the activity of the enzyme elastase. Wrinkles and sagging skin are the result of a breakdown in the skin’s elastic fibre network. The aim of this research is to identify the most promising material for suppressing the enzyme elastase from common four rose (Damask, Bishop, Autumn and Lafont) species in Vietnam, as well as to compare the bioactivities of fresh and dried petals. The obtained results showed that Damask and Bishop petal extracts had the highest antioxidant activity in the DPPH assay with IC50 = 10.08 and 10.07 μg/mL, respectively. Damask rose displayed not only an outstanding elastase inhibition with IC50 = 261.42 ± 0.8 μg/mL but also a high total polyphenol content (TPC) value of 149.49 mg GAE/g extract. These results indicate that the Rosa damascena petals could be used as valuable material for anti-aging product development based on the high TPC and elastase inhibitory activities.
Anti-aging, Antioxidant, Enzyme Elastase, Rosa damascena petals.